生殖中心与胸腺瘤患者的胸膜切除术后肌痛严重症有关
Hye Yoon Chung1,2, Ha Young Shin1, Young-Chul Choi1
1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
European journal of neurology
|November 1, 2023
概括
胸膜组织中生殖中心 (GC) 的存在可以预测胸膜瘤切除后肌痛严重症 (MG) 的发展. 患有甲状腺瘤组织中的GC患者患甲状腺瘤切除术后MG的发病率显著更高.
科学领域:
- 免疫学 免疫学 免疫学
- 神经学 神经学
- 病理学 病理学 病理学
背景情况:
- 发芽中心 (GCs) 存在于患有发芽瘤相关的骨髓灰质炎 (MG) 患者的胸膜组织中.
- 胸膜GCs对发育后胸膜切除术MG的预测价值仍然不清楚.
研究的目的:
- 为了调查GCs在胸腺瘤组织中的存在是否可以预测胸腺瘤切除后MG的发展.
主要方法:
- 追溯分析196名经历了胸腺瘤切除的非肌性患者.
- 胸膜组织的病理检查,以确定GCs (GC-阳性与GC-负组).
- 胸膜切除术后MG发病率的比较和风险因素的评估.
主要成果:
- 在21名患者 (GC阳性组) 中存在GC,在175名患者 (GC阴性组) 中不存在GC.
- 甲状腺切除术后的MG发生在33.3%的GC阳性患者和2.3%的GC阴性患者中 (p < 0.001).
- GC的存在和侵入性胸腺瘤是肌肉切除术后MG的显著风险因素.
结论:
- 胸膜GCs是开发后胸膜切除术MG的重要危险因素.
- 考虑在胸腺瘤患者中进行胸膜切除术后的MG,特别是那些患有胸膜GC的患者,即使没有先前存在的MG症状.
关键词:
发芽中心是生殖中心.肌痛性骨髓灰质炎 (Myasthenia Gravis) 是一个严重的疾病.有关风险因素的风险因素.甲状腺切除术 (thymectomy) 是一种切除术.蒂莫莫马马 (thymomaoma) 是一种疾病.更多相关视频
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