呼吸道病毒感染,包括COVID-19在固体器官移植中的感染
1Transplant Infectious Diseases, Ajmera Transplant Centre, University Health Network, University of Toronto, Toronto, ON, Canada.
Current opinion in organ transplantation
|November 1, 2023
概括
固体器官移植接受者面临呼吸道病毒的高风险. 在诊断和治疗SARS-CoV-2方面的进展为这些易受感染的患者管理其他呼吸道感染提供了新的希望.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 移植医学 移植医学 移植医学
背景情况:
- 呼吸道病毒感染对实体器官移植 (SOT) 接受者构成重大风险,导致发病率和死亡率增加.
- 包括SARS-CoV-2在内的呼吸道病毒对SOT接受者的影响是越来越多的研究领域.
- 了解病毒流行病学和宿主反应对于管理SOT患者至关重要.
研究的目的:
- 审查当前关于SOT接受者的呼吸道病毒的文献.
- 讨论SOT患者呼吸道病毒的流行病学,临床表现和诊断方法.
- 探索SOT接受者呼吸道病毒感染的预防和治疗策略的进展.
主要方法:
- 关于SOT接受者的呼吸道病毒最近研究的文献综述.
- 对诊断方法,临床结果和治疗干预措施的分析.
- 检查新的抗病毒药物,免疫疗法和疫苗.
主要成果:
- 更广泛地使用分子诊断提高了对SOT人口病毒影响的理解.
- COVID-19流行病研究为管理其他呼吸道病毒提供了见解.
- 呼吸系统病毒可以引起各种症状和并发症,包括全移植功能障碍.
结论:
- 在SOT接收者中有效管理呼吸道病毒需要全面的方法.
- 对于社区获得的呼吸道病毒,正在出现新的治疗和预防策略.
- 持续的研究对于改善面临病毒感染的SOT患者的结果至关重要.
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