声波辐射力脉冲成像与慢性性标记物的相关性在原生脏活检中
Gerry George Mathew1, Krishna Chaitanya Gunda2, K C Prakash3
1Department of Nephrology, SRM Medical College Hospital And Research Centre, Kattankulathur, Tamil Nadu, India-603203.
概括
声波辐射力脉冲 (ARFI) 超声波与脏活检慢性标志物没有相关性. 抗性指数 (RI) 显示出更好的预测值来评估慢性病进展.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 放射学 放射学是一门学科.
- 病理学 病理学 病理学
背景情况:
- 声波辐射力脉冲 (ARFI) 显示出对评估肝硬度的前景.
- 有限的数据存在于ARFI与慢性病 (CKD) 标志物在活检中的相关性.
研究的目的:
- 在超声波中确定ARFI值,并将其与脏活检慢性标志物相关联.
- 评估ARFI作为慢性病慢性病的非侵入性预测因子,与脏长度,抵抗性指数 (RI) 和皮层厚度相比.
主要方法:
- 在活检之前,250名患者接受了超声波 (ARFI,长,RI,皮质厚度).
- 脏活检幻灯片使用梅奥诊所的共识报告评分系统进行了分级.
主要成果:
- ARFI显示了与病理总得分 (r=-0.286) 的弱负相关性和与eGFR (r=0.279) 的弱正相关性.
- 抗性指数 (RI) 与组织学慢性 (r=0.416) 的正相关性比ARFI,长或皮层厚度更强.
结论:
- 在活检中,ARFI不是病态慢性病理的可靠指标.
- 与ARFI相比,RI是原生脏活检中慢性病的更有效的非侵入性预测因子.
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