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在非心脏手术后的术后结果中性别差异
Kai Yi Wu1, Xiaoming Wang2, Erik Youngson2
1Mazankowski Alberta Heart Institute, Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada.
PloS one
|November 1, 2023
概括
男性性别是非心脏手术后增加死亡率和再入院的独立风险因素,特别是在65岁以下的患者中. 男性性别对结果的影响随着年龄的增长而减少.
科学领域:
- 外科手术 手术手术
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 手术结果中的性别差异尚未完全理解.
- 非心脏手术带有死亡率和发病率的风险.
- 识别独立的风险因素对于患者护理至关重要.
研究的目的:
- 调查性别作为非心脏手术后死亡率和发病率的独立风险因素.
- 分析按性别分层的短期和长期结果.
- 探索年龄对与性别相关的外科手术结果的影响.
主要方法:
- 在加拿大阿尔伯塔省 (2008-2019) 使用链接的行政数据库进行回顾性队列研究.
- 包括接受45种非心脏手术的患者.
- 多变量逻辑回归调整为年龄,性别,手术类型,查尔森并发症指数和修订的心脏风险指数.
主要成果:
- 男性性别是30天,6个月和1年死亡率的重要预测因素 (aORs从1.25到1.26不等).
- 男人性别也预测了30天,6个月和1年的再入院 (aORs从1.06到1.12不等).
- 与年轻患者相比,65岁及以上的患者男性性别对结果的影响较小.
结论:
- 接受非心脏手术的男性患者面临死亡率和再入院的风险较高,独立于其他风险因素.
- 男性性别对不良结果的影响在年轻的 (<65岁) 手术患者中更为显著.
- 性别和年龄都是预测非心脏手术后临床结果的重要因素.
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