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Updated: Jul 12, 2025

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
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冷血脊椎动物进化了有组织的生殖中心样结构

Yasuhiro Shibasaki1,2, Sergei Afanasyev3, Alvaro Fernández-Montero1

  • 1Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Science immunology
|November 1, 2023
PubMed
概括

外热脊椎动物,如鱼,拥有特殊的脏结构,称为MMC相关的淋巴结合物 (M-LAs),促进适应性免疫反应,与哺乳动物中发现的生殖中心类似地起作用.

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