一位66岁的妇女,左眼视力扭曲两周,左眼视力扭曲两周
Shane Griffin1, H Richard McDonald1,2, Anita Agarwal1,2
1California Pacific Medical Center (CPMC), San Francisco, CA.
Retinal cases & brief reports
|November 1, 2023
概括
本病例报告详细介绍了一名患有转移性黑色素瘤的患者,该患者患有MEK抑制剂相关视网膜病变 (MEKAR) 和并发性轨道转移. 这些发现强调了多式成像对于诊断和监测这些罕见疾病的重要性.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 转移性黑色素瘤可以扩散到各种器官,包括轨道.
- MEK 抑制剂用于治疗转移性黑色素瘤,但可能导致眼部副作用.
- 与MEK抑制剂 (MEKAR) 相关的视网膜病变是一种已知的但不太常见的并发症.
研究的目的:
- 在患有转移性黑色素瘤的患者中呈现同时轨道转移和MEK抑制剂相关视网膜病变的病例.
- 描述这种罕见的并发性疾病的临床表现,诊断成像和管理.
主要方法:
- 一个66岁的女性患有转移性黑色素瘤,接受MEK抑制剂治疗的病例报告.
- 使用了临床检查,光学连贯断层扫描 (OCT) 和磁共振成像 (MRI).
- 记录了患者的病史和治疗反应.
主要成果:
- 患者在开始MEK抑制剂治疗后出现双边视力模糊和血清性视网膜脱落 (MEKAR).
- 轨道转移导致一只眼睛的胆管皮折叠和变形症.
- 虽然一些视网膜脱落得到解决,但叶病变仍然存在,患者后来发展了额外的转移.
结论:
- 同时的轨道转移和MEK抑制剂相关的视网膜病变可能发生在转移性黑色素瘤患者中.
- 多模式成像对于准确诊断和监测这些复杂的眼睛和转移性疾病至关重要.
- 及时识别和管理对于患者的治疗结果至关重要.
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