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Updated: Jul 12, 2025

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用于免疫检查点降解疗法的DNA适合剂激活的共价LYTAC

Yuqing Li1, Xueliang Liu2, Lu Yu2,3

  • 1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou 215123, China.

Journal of the American Chemical Society
|November 1, 2023
PubMed
概括

新的 lysosome-targeting chimera (LYTAC) 疗法降低了免疫检查点 PD-L1,从而增强了抗瘤反应. 与抗体疗法相比,这种共价LYTAC方法提供了更好的疗效和减少了炎症.

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