最大缩加速的诊断准确度,以检测周围动脉疾病
Siem A Willems1, Saskia G Dolfing1, Rob C van Wissen1
1Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Journal of vascular surgery
|November 1, 2023
概括
最大缩加速 (ACCmax) 在诊断外围动脉疾病 (PAD) 中显示出高准确性,即使是在糖尿病 (DM) 和慢性病 (CKD) 的患者中也是如此. 这种多普勒衍生参数为PAD检测提供了一个有前途的新临床测试.
科学领域:
- 血管医学 血管医学
- 诊断成像 诊断成像 诊断成像
- 生物医学工程 生物医学工程
背景情况:
- 在患有糖尿病 (DM) 和慢性病 (CKD) 的患者中,由于中枢动脉化 (MAC),诊断外围动脉疾病 (PAD) 是具有挑战性的.
- 在这些患者群体中,传统的床边测试,如脚-手腕指数 (ABI) 和脚-手腕指数 (TBI),往往不足.
- 最大缩加速 (ACCmax),一个多普勒衍生参数,呈现了一个潜在的新诊断工具.
研究的目的:
- 评估ACCmax在检测PAD中的诊断性能.
- 评估ACCmax作为PAD的床边测试的实用性.
- 为了确定ACCmax的准确性是否受到DM和CKD等并发症的影响.
主要方法:
- 一项回顾性队列研究包括340名疑似PAD患者.
- 从后,前和关动脉进行了ACCmax测量.
- 计算机断层扫描血管造影作为PAD诊断的参考标准.
主要成果:
- 在所有测量的动脉中,ACCmax表现出色的诊断性能.
- 对于前额动脉,灵敏度为94%,特异性为97%,AUC为0.984.
- 即使在DM或CKD患者的亚组中,诊断准确度仍然很高.
结论:
- ACCmax是诊断PAD的一个高度准确的参数.
- 它的诊断性能在中枢动脉化患者,包括DM和CKD患者中没有受到影响.
- ACCmax是一个可靠的床边测试,用于检测PAD.
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