遗传决定性和半球影响在头发螺旋形成
Marjolaine Willems1, Quentin Hennocq2, Sara Tunon de Lara3
1Department of Medical Genetics, Montpellier University Hospital, Montpellier, France.
Journal of stomatology, oral and maxillofacial surgery
|November 1, 2023
概括
头发旋转方向受遗传影响,双胞胎表现出类似的模式. 地理位置影响旋转方向,反时针方向的模式在南半球更常见.
科学领域:
- 人类遗传学 人类遗传学
- 发育生物学是发展生物学.
- 人类解剖学 人类解剖学
背景情况:
- 遗传基础和环境对头发旋横向性和旋转方向的影响在很大程度上是未知的.
- 头发旋转模式,就像其他旋转现象一样,可能会受到地理变化的影响.
研究的目的:
- 为了研究头发旋转模式形成的遗传基础.
- 为了比较半球之间的头发旋转方向,并探索潜在的地理影响.
主要方法:
- 追溯分析北半球 (法国) 和南半球 (智利) 儿童的头发旋转 (顺时针/反时针) 和位置.
- 同性双胞胎的比较,以评估对旋转方向的遗传影响.
- 使用后勤模型和几率比率 (OR) 的统计分析来比较双胞胎和半球之间的方向偏好.
主要成果:
- 双胞胎对相同的头发螺旋旋转方向 (OR ≠ 1, p = 0.017) 呈现出统计学上显著的偏好.
- 在模拟双胞胎比较中,北半球和南半球的人群都更喜欢相同方向的旋转 (ORs < 1).
- 与北半球 (OR = 0.04,p < 0.001) 相比,在南半球 (OR = 0.28) 发生的反时针方向的头发旋转明显更频繁.
结论:
- 发的形成似乎是一个由基因决定的过程,可能受到外部环境因素的调节.
- 地理位置可能会显著地影响面发育,正如头发旋转模式的半球差异所表明的那样.
- 建议进行大规模的流行病学研究来验证这些发现,并探索受地理影响影响的发育机制.
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