冠状动脉疾病的移植前查:在改变实践之前需要数据
John S Gill1, Steven J Chadban2
1Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada.
Kidney international
|November 1, 2023
概括
移植计划正在减少冠状动脉疾病查,原因是死亡率下降和高测试负担. 在改变长期存在的查方案之前,需要更多的临床试验.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 移植 移植 移植 移植
背景情况:
- 周周移植心血管死亡率的下降.
- 移植前检测的负担越来越大.
- 对冠状动脉疾病查在移植候选人的有效性存在担忧.
研究的目的:
- 审查目前关于冠状动脉疾病查在移植候选人的证据.
- 确定需要进一步研究的领域.
- 在改变既定查范式之前,倡导进行临床试验.
主要方法:
- 审查最近的科学陈述和指南从病:改善全球结果和美国心脏协会.
- 分析目前关于移植受体心血管风险的证据.
- 论证对足够强大的临床试验的必要性.
主要成果:
- 目前的证据总结了现有知识,但突出了理解的差距.
- 在许多移植计划中,查协议的降级趋势存在.
- 目前查方法的有效性仍然令人担忧.
结论:
- 在没有强大的临床试验数据的情况下,不应该放弃对移植候选人的冠状动脉疾病的既定查范式.
- 进一步的研究至关重要,以指导基于证据的查协议的修改.
- 与有效的风险评估平衡测试负担至关重要.
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