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电能和氧化石墨烯对Enterococcus faecalis生物膜的联合作用

Myung-Jin Lee¹, Mi-Ah Kim², Kyung-San Min^2,3,4

¹Department of Conservative Dentistry, School of Dentistry, Seoul National University.

Dental materials journal

|November 1, 2023

概括

电能与石墨烯氧化物 (GO) 结合,显著增强了二 (NaOCl) 对Enterococcus faecalis生物膜的抗菌作用. 这种组合显示出改善根管灌协议的潜力.

科学领域:

生物医学工程生物医学工程
微生物学微生物学
材料科学材料科学材料科学

背景情况:

菌 (Enterococcus faecalis) 是持续根管感染中常见的病原体.
由E. faecalis形成的生物膜对传统的内牙治疗提出了重大挑战.
需要新的策略来有效地根除E. faecalis生物膜.

研究的目的:

研究电能和石墨烯氧化物 (GO) 对Enterococcus faecalis (E. faecalis) 生物膜的协同抗菌作用.
评估这种组合疗法在根管灌方面的潜力.

主要方法:

使用殖民地形成单位和晶体紫色染色来评估细菌活力.
通过扫描电子显微镜检查的生物膜形态.
使用传输电子显微镜 (TEM) 观察到的细菌器官损伤.
处理组的比较:电能+0.2%的低化 (NaOCl) 与0.2%的单独NaOCl相比,并添加GO.

主要成果:

与0.2%的NaOCl相结合的电能显著降低了E. faecalis的生存能力和生物膜生物质,与单独的NaOCl相比.
添加GO证明了与0.5%NaOCl.Cl.相比的抗菌功效.
在电能和GO治疗组中,TEM揭示了细菌细胞膜的显著损伤.

结论:

电能和GO的组合增强了NaOCl对E. faecalis生物膜的抗菌活性.
这种协同方法为增强根管消毒协议提供了一个有希望的策略.

关键词:

生物膜是一种生物膜.电力能源电力能源菌 (Enterococcus faecalis) 是一种菌.石墨烯氧化物石墨烯氧化物

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