与HSP90结合的PER2通过抑制IKK/NF-κB通路和PD-L1表达来增强对口腔状细胞癌的免疫反应

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Zhiwei Zhang1, Deping Sun2, Hong Tang1

  • 1Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Journal for immunotherapy of cancer
|November 1, 2023
PubMed
概括

核心时钟基因Period2 (PER2) 抑制了口腔状细胞癌 (OSCC) 中的编程死亡配体1 (PD-L1). 针对PER2进行抗PD-L1免疫疗法,通过促进T细胞透,增强了抗瘤效果.

关键词:
头部和部的新生瘤.免疫疗法 免疫疗法瘤逃脱是什么意思

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