9-O-berberrubine碳酸盐的结构酵母α-葡萄糖酶抑制活性关系

Duy Vu Nguyen1, Kowit Hengphasatporn2, Ade Danova1,3

  • 1Department of Chemistry, Faculty of Science, Center of Excellence in Natural Products Chemistry, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.

Scientific reports
|November 2, 2023
PubMed
概括

新的柏柏鲁宾衍生物显示出强大的酵母α-葡萄糖酶抑制,表现优于阿卡尔. 化合物9,26,28和33是具有竞争性抑制机制的有希望的非细胞毒性抗糖尿病候选药物.

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