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Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
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通过胆固醇转移促进脑器官成熟

Dong Shin Park1,2, Tatsuya Kozaki1, Satish Kumar Tiwari1

  • 1Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.

Nature
|November 2, 2023
PubMed
概括

研究人员通过添加原始巨细胞来开发出足够微质的大脑器官. 这些工程微质 (iMicro) 调节神经元发育,并通过脂质运输促进轴突生长,从而推进大脑器官模型.

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