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Updated: Jul 12, 2025

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
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支持深度学习的自然语言处理用于识别定向的药理动力学药物相互作用

Joel Zirkle1, Xiaomei Han1, Rebecca Racz1

  • 1Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, WO Bldg 64 Rm 2078, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA.

BMC bioinformatics
|November 2, 2023
PubMed
概括

这项研究引入了一种新方法,可以从文本中自动识别药理学药物相互作用 (DDI) 的方向. 该模型在PK DDI句子中准确地区分了对象和沉剂药物.

关键词:
指向性 指向性是指向性的.药物相互作用 药物相互作用自然语言处理自然语言处理.药物动力学 药物动力学变压器语言模型

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