在黎巴嫩人口的两个样本中发现阿片类药物使用障碍:规模验证和与睡眠和情绪障碍的相关性
Karam Chamoun1,2,3, Joseph Mouawad1,2, Pascale Salameh4,5,6,7
1Faculty of Pharmacy, Saint Joseph University of Beirut, Beirut, Lebanon.
BMC psychiatry
|November 2, 2023
概括
阿拉伯阿片类药物风险工具 (ORT-OUD) 已被验证用于查黎巴嫩阿片类药物使用障碍 (OUD) 风险. 该工具有助于在黎巴嫩人口中早期发现和管理OUD.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 公共卫生 公共卫生
背景情况:
- 阿片类药物使用障碍 (OUD) 构成了重大的公共卫生挑战.
- 查工具对于危险人群的早期检测和干预至关重要.
- 片风险工具 (ORT-OUD) 是一个验证的自我报告措施,用于评估OUD风险.
研究的目的:
- 为黎巴嫩人口翻译和验证阿拉伯版本的ORT-OUD.
- 评估阿拉伯语ORT-OUD在患有OUD病史的患者中的临床有效性.
- 为了评估在黎巴嫩OUD风险的流行,使用验证的阿拉伯ORT-OUD.
主要方法:
- 一项涉及黎巴嫩人口581名参与者的横截面研究.
- 使用阿拉伯版本的ORT-OUD和酒精,吸烟和物质参与查测试 (ASSIST).
- 采用主要组件分析用于构造有效性和对应性分析用于合和标准有效性.
主要成果:
- 阿拉伯语ORT-OUD表现出良好的构造有效性,项目汇聚到四个因素,解释了68.2%的差异.
- 使用ORT-OUD估计OUD风险的患病率为14.5%,使用ASSIST-阿片类药物估计为6.54%.
- 在ORT-OUD得分和各种ASSIST分量表之间发现了显著的相关性,以及家庭/个人吸毒史,失眠和焦虑.
结论:
- 阿拉伯版本的ORT-OUD是一个有效和可靠的工具,用于查黎巴嫩人口中OUD风险.
- 这项验证是改善黎巴嫩OUD检测和管理的关键一步.
- 这些发现强调了OUD风险与诸如药物使用史,睡眠障碍和情绪障碍等因素之间的关联.
相关概念视频
Substance Use Disorders Affecting Sleep
174
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
174
Sedatives and Hypnotics Drugs: Miscellaneous Agents
182
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
182
CNS Depressants: Barbiturates and Benzodiazepines
288
CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
288
Insufficient Sleep and Sleep Deprivation
148
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
148
Narcolepsy
117
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
117
Management of Insomnia
259
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
259


