细菌性脑膜炎中的跨骨多普勒超声波:系统性审查
Laurence Kristoffer J Batino1, Mark Timothy T Cinco1, Jose C Navarro1,2
1Department of Neurology, Zeenat Qureshi Stroke Institute, Jose R. Reyes Memorial Medical Center, Manila, Philippines.
Journal of clinical ultrasound : JCU
|November 2, 2023
概括
体多普勒 (TCD) 超声波检测到细菌性脑膜炎患者的脑内血管病变,与糟糕的结果相关. 这种具有成本效益的工具有助于诊断和预后,改善患者管理.
科学领域:
- 神经学 神经学
- 诊断成像 诊断成像 诊断成像
- 传染性疾病 传染性疾病
背景情况:
- 细菌性脑膜炎是一个危及生命的全球健康问题,每年有超过120万例.
- 内血管病是细菌性脑膜炎的一个重要但经常被忽视的并发症.
- 跨骨多普勒 (TCD) 超声波为检测内血管病变提供了一种可靠的方法.
研究的目的:
- 系统地审查TCD在诊断和管理细菌性脑膜炎中的实用性.
- 评估TCD在识别内血管病变中的作用及其与患者结果的相关性.
- 评估TCD在预测细菌性脑膜炎的预后方面的有效性.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 分析了涉及患者的观察性研究,其中包括CSF证明的细菌脑膜炎.
- 评估了TCD参数变化,神经成像相关性和功能结果.
主要成果:
- 纳入了9项涉及492名参与者的研究.
- 内动脉狭窄,特别是MCA,是最常见的TCD发现 (50%-82%).
- 异常的TCD发现与70%的不良结果风险增加和缺血的主要神经影像发现 (33%) 相关.
结论:
- 在细菌性脑膜炎患者中,TCD揭示了脑血流变化,与成像和不良结果相关.
- TCD有助于诊断脑膜炎的后果并预测患者的预后.
- 细菌脑膜炎 (TCD) 是一种具有成本效益和可靠的工具,用于检测细菌脑膜炎中的血管病变,并有可能改善管理策略.
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