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Updated: Jul 12, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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抗瘤缺氧增强的尼特罗伊米达衍生物:设计,合成,抗瘤活性,分子对接研究和QSAR研究

Aya M Almatary1,2, Walaa M El Husseiny1, Khalid B Selim1

  • 1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Drug development research
|November 2, 2023
PubMed
概括

针对低氧瘤的新型胺酸基药物显示出强大的抗增殖和放射敏感作用. 自由醇组对活性至关重要,化合物21b被确定为一个有前途的循环素依赖激酶2 (CDK2) 抑制剂,可诱导细胞亡和细胞循环停止.

关键词:
在QSAR中使用QSAR.癌症 癌症 癌症 癌症 癌症缺氧 缺氧是指缺氧的情况.尼特罗伊米达二醇的使用方法氧沙醇是一种氧沙醇.三醇三醇的使用方法

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