在一个免疫能力强的年轻成年人中,主要的中灰区淋巴瘤
Aisyah Wirdah1, Yenny Dian Andayani, Mediarty Syahrir
1Department of Internal Medicine, Faculty of Medicine Universitas Sriwijaya - Mohammad Hoesin General Hospital, Palembang, Indonesia. aisyahwirdah297@gmail.com.
Acta medica Indonesiana
|November 2, 2023
概括
一名怀疑患有肺外结核的28岁男子被诊断出患有原发性中间灰色区淋巴瘤 (PMGZL). 用R-CHOP化疗治疗导致完全反应,突出显示了它对这种罕见淋巴瘤的有效性.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 病理学 病理学 病理学
背景情况:
- 一名28岁的男性呈现出快速增长的宫和腹淋巴结核病和体重减轻.
- 最初的诊断认为是肺外结核 (EPTB),但由于异常呈现和广泛的淋巴腺病变,需要进一步调查.
研究的目的:
- 报告一例最初误诊的初级中间灰色区域淋巴瘤 (PMGZL) 病例,并评估R-CHOP化疗的疗效.
主要方法:
- 临床检查显示了宫,关节和关节区域的显著淋巴腺病变.
- 实验室测试显示炎症标志物 (WBC,LED) 和D-二次数的升高.
- 脑电图扫描显示中,副,周围淋巴结扩大,还有脏病变.
- 通过免疫组织化学 (IHC) 进行的活检证实了PMGZL (CD20+,CD30+,CD79a+,MUM1+,Ki67 80-90%,BCL6+,BCL2+).
主要成果:
- 免疫组织化学证实了原发性中间灰色区域淋巴瘤的诊断.
- 患者接受了R-CHOP化疗 (里图西马布,环胺,多克索鲁比辛,文克里斯,普雷德尼松).
- 患者在R-CHOP治疗方案中取得了完全的反应.
结论:
- 主要的中间灰色区域淋巴瘤可能伴有广泛的淋巴腺病变,并且可能最初被误诊.
- 在PMGZL中,R-CHOP化疗是实现完全缓解的有效治疗方案.
更多相关视频
11:15Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts
Published on: September 1, 2018
8.0K
08:44Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
2.5K
相关概念视频
01:15Secondary Lymphoid Organs
1.5K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
1.5K
01:23Cells of the Adaptive Immune Response
999
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
999