脱发症中的肠道和皮肤微生物组:关联和干预措施
Alexis E Carrington1, Jessica Maloh2, Yvonne Nong2,3,4
1Dr. Carrington is with the Department of Dermatology at George Washington School of Medicine and Health Sciences in Washington, DC.
The Journal of clinical and aesthetic dermatology
|November 2, 2023
概括
改变的肠道和皮肤微生物组与脱发症 (如脱发症) 相关. 调节这些微生物组,可能通过便移植或益生菌,对头发生长治疗有希望.
科学领域:
- 微生物组研究的研究.
- 皮肤病学 皮肤病学
- 三学是指三学的学科.
背景情况:
- 肠-皮肤轴越来越多地被认为是它在各种健康状况中的作用.
- 脱发症,包括诸如脱发区域性脱发症和雄激素脱发症等疾病,影响全球数百万人.
- 了解肠道微生物群,皮肤微生物群和毛囊健康之间的相互作用至关重要.
研究的目的:
- 审查关于脱毛症中肠皮肤连接的现有文献.
- 总结了针对肠道或皮肤微生物群发育的干预措施.
- 探索微生物组调制在治疗不同形式的脱发症方面的潜力.
主要方法:
- 进行了全面的PubMed搜索,以确定相关的研究.
- 研究的重点是肠道和皮肤微生物群,与大发性脱发症,雄激素脱发症,全身脱发症,中心离心痕脱发症和平相联系.
- 包括标准优先考虑人类和动物研究,不包括非英语文章和仅关于补充疗法的文章.
主要成果:
- 有证据表明,头皮,毛囊和肠道微生物组的变化与各种脱发症类型有关.
- 微生物组失生症似乎在脱发的病理生理学中发挥着作用.
- 针对失生症的干预措施,如便微生物群移植和益生菌,显示出潜在的治疗益处.
结论:
- 肠道,头皮和毛囊中的失能症与各种脱发形式的发展有关.
- 准微生物组失生症为治疗和管理脱发提供了一个有希望的途径.
- 需要进一步的高质量研究,使用更大的队列来巩固这些发现,并阐明具体的干预效应.
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