嗅觉和味觉功能障碍,评估和对COVID-19患者的生活质量的影响:一项多中心研究
Abdulaziz Saud AlEnazi1, Maha Abdullah Alharbi2, Danah Hamdan Althomaly2
1Departments ofOtolaryngology-Head and Neck surgery.
Annals of medicine and surgery (2012)
|November 2, 2023
概括
COVID-19对沙特患者,特别是女性和40岁以下患者的嗅觉和味觉有重大影响. 这些化学感官功能障碍会影响生活质量,尽管在8天内恢复是常见的.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 公共卫生 公共卫生
背景情况:
- 化学感官功能障碍,包括嗅觉和味觉丧失,是 COVID-19 的常见症状.
- 这些症状的发病率和表现在不同的全球人口中可能有很大差异.
研究的目的:
- 在沙特阿拉伯的COVID-19患者中确定嗅觉和味觉功能障碍的患病率.
- 评估与这些化学感官变化相关的恢复时间和对生活质量 (QoL) 的影响.
主要方法:
- 一项多中心观察性研究涉及沙特阿拉伯的1734名实验室确诊的COVID-19患者.
- 通过在线调查收集的数据,使用经过验证的嗅觉和味觉功能障碍问卷和QOL评估 (sQOD-NS).
主要成果:
- 在56.5%的患者中报告了化学感官功能障碍,女性 (66.2%) 和40岁以下 (62.2%) 的女性更高.
- 嗅觉功能障碍的恢复率为77.2%,口味功能障碍的恢复率为71.6%,通常在8天内.
- 观察到对 QoL 的显著负面影响,特别是在女性中 (P<0.001).
结论:
- 沙特阿拉伯人的化学感官功能障碍患病率与欧洲的数据一致,但超过亚洲的数据,这表明种族差异.
- 这些功能障碍显著损害了QoL,并可能是COVID-19的早期指标.
- 症状恢复数据有助于患者咨询和预后;建议进行长期研究.
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