在COVID-19大流行后的长期认知功能障碍:叙事审查
Sanobar Shariff1,2, Olivier Uwishema1,3,4, Jocelyn Mizero1,5
1Oli Health Magazine Organization, Research and Education, Kigali, Rwanda.
Annals of medicine and surgery (2012)
|November 2, 2023
概括
长期的COVID可能会导致严重的认知障碍,影响记忆力和注意力. 对于有效的神经认知评估和治疗来改善患者的生活质量,需要进一步的研究.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 由SARS-CoV-2引起的COVID-19导致长期COVID/后COVID-19综合征.
- 认知功能障碍,包括疲劳和脑雾,是常见的和使人虚弱的症状.
- 认知障碍的机制是多方面的,涉及中枢和外枢神经系统的原因,但仍然不清楚.
研究的目的:
- 审查COVID-19后长期认知障碍的潜在机制.
- 探索与早期干预的关联和潜在的预防策略.
- 了解对患者生活质量的影响.
主要方法:
- 在主要数据库 (Medline,PubMed,Scopus,Ovid) 中进行了系统的文献搜索.
- 纳入标准集中在详细介绍SARS-CoV-2感染后认知功能障碍的文章上.
- 排除标准删除了对其他认知功能障碍原因的研究;提取和分析了相关数据.
主要成果:
- 与COVID-19相关的认知功能障碍的确切病原体尚不清楚,这阻碍了管理策略.
- 建议的机制包括直接的血脑屏障损伤,全身炎症,缺氧和重症监护室 (ICU) 停留.
- 目前还没有制定最终的管理准则.
结论:
- 长期认知障碍是影响COVID-19后生活质量的重大全球挑战.
- 对所有COVID-19患者来说,全面的评估和干预至关重要,特别是那些有先前认知问题的患者.
- 建议进行进一步的研究,以制定及时有效的神经认知评估和治疗计划.
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