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以前的癌症病史和适合进行移植的情况
Germaine Wong1,2,3, Wai H Lim4
1Sydney School of Public Health, University of Sydney, Camperdown, NSW, Australia.
Clinical kidney journal
|November 2, 2023
概括
癌症幸存者的脏移植资格是复杂的. 由于癌症治疗方法的改进,平衡癌症复发风险和移植效益的个性化决策现在更加合理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 在瘤学瘤学.
- 移植医学 移植医学
背景情况:
- 移植是衰竭的首选治疗方法.
- 对有癌症史的患者进行移植资格评估涉及癌症复发风险和免疫抑制的复杂考虑.
- 癌症治疗和基因组学的进步需要重新评估移植资格标准.
研究的目的:
- 审查移植接受者的癌症流行病学.
- 探索癌症治愈概率,复发风险和结果如何影响癌症幸存者的移植决策.
- 讨论共同决策在管理脏移植候选人与癌症病史.
主要方法:
- 文献综述总结了移植接受者的癌症流行病学.
- 探索影响癌症幸存者的移植决策的因素.
- 讨论共享决策模式和患者价值观.
主要成果:
- 移植后癌症复发带来高死亡率,可能会减少移植的好处.
- 由于新型疗法而改善的无癌症生存率支持个性化移植适合性评估.
- 共享决策对于纳入患者偏好和价值观至关重要.
结论:
- 对癌症幸存者的个性化移植适合性决定越来越多地得到癌症治疗和基因组学的进步的支持.
- 为了平衡癌症复发的风险与移植的好处,需要仔细考虑癌症生物学,治疗选择和预后因素.
- 临床医生和患者之间的共同决策对于最佳管理和尊重患者价值观至关重要.
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