超脂血症和糖尿病视网膜病变 (DR) 中的降脂疗法: 1993-2023年的一项文献计量研究和可视化分析
Haishan Tan1,2, Xiangyu Fu1,2, Yongjiang Chen3
1Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Heliyon
|November 2, 2023
概括
糖尿病视网膜病变 (DR) 的脂质研究正在不断增长,研究重点是降脂药物,如纤维酸和他类药物. 未来的研究将探索脂质生物标志物和DR治疗的药物输送.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
背景情况:
- 糖尿病视网膜病变 (DR) 是糖尿病的一种神经退行性并发症,受高血糖症,高脂血症和高血压的影响.
- 虽然葡萄糖和血压的作用是已知的,但身体脂肪和降脂药对DR的影响是最近的研究重点.
- 图书统计分析可视化了DR相关脂质研究中的贡献,趋势和热点.
研究的目的:
- 分析研究人员,组织和国家在1993年至2023年DR相关脂质研究中的贡献.
- 确定糖尿病视网膜病变和脂质代谢领域的研究热点和趋势.
- 为DR-脂质研究的演变和未来方向提供见解.
主要方法:
- 从1993年到2023年对1402篇出版物的图书统计分析.
- 从科学网络核心集合中提取的数据.
- 使用VOSviewer和CiteSpace软件进行的分析.
主要成果:
- 三十年来,DR相关的脂质研究持续增长,近年来有显著增加.
- 美国,中国,日本,澳大利亚和英国是领先的国家;糖尿病研究和临床实践和糖尿病护理是关键出版物.
- 关键的研究领域包括氧化应激,糖尿病黄斑和脂质过氧化,重点是降脂疗法.
结论:
- 与DR相关的脂质研究集中在北美,亚洲,大洋洲和欧洲,重点是降脂疗法.
- 降脂药物表现有前途,但它们对视网膜病变的影响可能与脂质谱的变化无关.
- 进一步的随机临床试验和对脂质生物标志物和药物输送的研究建议用于DR治疗.
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