心率在休息和应对压力的变化:血液透析和腹腔透析患者之间的比较研究
Danai Faitatzidou1, Konstantina Dipla2, Marieta P Theodorakopoulou1
1Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki GR54642, Greece.
Experimental biology and medicine (Maywood, N.J.)
|November 2, 2023
概括
自主神经系统 (ANS) 功能障碍在末期脏疾病 (ESKD) 中很常见. 这项研究发现血液透析 (HD) 和腹腔透析 (PD) 患者之间的心率变化 (HRV) 类似,除了在HD患者体力压力后ANS恢复受损.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 自主神经科学 自主神经科学
背景情况:
- 末期病 (ESKD) 与心律失常和突然死亡的死亡率增加有关.
- 自主神经系统 (ANS) 功能障碍是ESKD患者心律失常背景的一个重要因素.
- 心率变化 (HRV) 是 ANS 功能的一个关键指标.
研究的目的:
- 为了比较血液透析 (HD) 和腹腔透析 (PD) 患者之间通过HRV指数评估的ANS功能.
- 评估HD和PD患者对精神和身体刺激的HRV反应.
- 为了确定与透析方式相关的ANS功能中的潜在差异.
主要方法:
- 一项比较研究涉及34名HD患者,34名PD患者和17名健康对照人群,根据年龄,性别和透析年龄进行了匹配.
- 使用Finometer-PRO在休息状态下和在ANS刺激动作 (静止,心智算术,坐立,握手练习) 期间持续监测心率.
- 对线性和非线性HRV指数的分析,包括RMSSD,SD1,SD2和DFA-α1/α2.2.
主要成果:
- 在休息状态下,在大多数HRV指数中没有观察到HD和PD患者之间的显著差异,DFA-α1除外,PD患者的DFA-α1比对照患者低.
- 在心理算术和身体压力测试期间,HD和PD组之间的HRV指数通常相似.
- 在坐立测试后,与休息相比,HD患者的RMSSD,SD1,SD2和DFA-α2显著增加,表明身体压力后ANS功能恢复的潜在损害,PD患者没有观察到相同程度的身体压力.
结论:
- 虽然HRV在休息和刺激期间评估的整体ANS功能在HD和PD患者之间没有显著差异,但在体力炼后ANS功能恢复方面存在微妙差异.
- 与腹腔透析患者相比,血液透析患者可能在应对身体压力时恢复正常的自主神经系统功能方面遇到更大的困难.
- 这些发现表明透析方式可能对ESKD患者的ANS功能恢复模式产生轻微影响.
相关概念视频
Hemodialysis III: Nursing Management
25
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
25
Hemodialysis II: Procedure and Complications
26
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
26
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
26
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
26
Dialysis
330
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
330
Hemodialysis I: Introduction
36
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
36
Regulation of Heart Rates
1.8K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
1.8K


