鱼和欧米茄-3脂肪酸:心血管结果和认知功能的性别和种族差异
Francine K Welty1, Ralph Daher2, Mahdi Garelnabi3
1Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston (F.K.W.).
Arteriosclerosis, thrombosis, and vascular biology
|November 2, 2023
概括
食鱼和omega-3脂肪酸,如EPA和DHA,可能有助于预防心血管疾病 (CVD) 和认知衰退,在不同性别和种族中观察到好处.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 神经科学是一个神经科学.
背景情况:
- 心血管疾病 (CVD) 和认知能力下降是与衰老相关的重大健康挑战.
- 在全球范围内,痴呆症影响着数百万人,心脏病是导致死亡的主要原因.
研究的目的:
- 审查鱼和omega-3脂肪酸 (EPA和DHA) 对心血管疾病和认知衰退的预防作用的性别和种族差异.
- 综合前性研究和随机对照试验的发现.
主要方法:
- 对研究鱼类摄入量和血omega-3水平的前性研究的分析.
- 对EPA和DHA补充剂用于预防心血管疾病和认知衰退的随机对照试验的综述.
主要成果:
- 较高的鱼类摄入量和血EPA/DHA水平与女性和黑人患者心血管疾病风险较低有关.
- 补充EPA和DHA在心血管疾病预防小组 (黑人,亚洲人) 和女性认知衰退中显示出好处.
- DHA似乎比EPA更有益,特别是当补充剂在认知能力下降之前开始时.
结论:
- 终身摄入鱼类和欧米茄-3脂肪酸与心血管疾病和认知能力下降的风险降低有关.
- 补充EPA和DHA提供了预防性益处,特别是在特定的人口统计和条件下.
- 饮食干预是预防疾病的潜在成本有效策略,需要进一步研究和临床考虑.
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