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在体外培养的肌肉细胞来源于肌肌触发点

Lin Liu^1,2, Qiang-Min Huang^2,3, Qing-Guang Liu⁴

¹School of Sport and Health, Nanjing Sport Institute, Nanjing, China.

Acupuncture in medicine : journal of the British Medical Acupuncture Society

|November 2, 2023

概括

肌肉纤维中的收缩结节与肌肌触发点 (MTrPs) 相关,在细胞培养物中保持其结构. 然而,它们的恢复与乙胆没有明确的联系.

科学领域:

肌肉生理学肌肉生理学
细胞生物学细胞生物学
疼痛研究疼痛研究

背景情况:

肌肌触发点 (MTrPs) 与肌肉纤维中可触摸的紧张带有关.
这些与MTrP相关的结构的精确的体外形态和行为尚未完全理解.

研究的目的:

为了研究肌肉纤维中的收缩结节在肌肌触发点的体外存在和形态.
评估这些结节对特定生化剂的反应.

主要方法:

使用机械伤害和古怪的运动在老鼠的胃半腹肌中建立肌肌触发点 (MTrP) 模型.
在MTrP和对照组单个肌肉纤维的细胞培养室内.
将MTrP细胞暴露在乙胆酶和控制细胞暴露在乙胆中,以观察形态变化.

主要成果:

来自MTrP部位的培养肌肉纤维表现出持续的大型收缩结节,其中一些具有变形形态.
无论是乙胆化酶还是乙胆暴露,都没有诱导各自肌肉纤维制剂的显著形态变化.

结论:

肌肉纤维与肌肌触发点相关,保持了收缩结节形态in vitro.
乙胆在这些收缩结节的恢复或维持中的作用仍然未确定.

关键词:

乙烯基胆是一种细胞培养培养的细胞培养.收缩性结节收缩性结节肌筋关触发点是指肌筋关的触发点.病理生理学病理生理学

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