在患有IgA脏病的患者中进行Sibeprenlimab的第二阶段试验

Mohit Mathur1, Jonathan Barratt1, Bobby Chacko1

  • 1From Visterra, Waltham, MA (M.M., J.Y., B.J.G.P.); John Walls Renal Unit, Leicester General Hospital, Leicester, United Kingdom (J.B.); Nephrology and Transplantation, John Hunter Hospital and University of Newcastle, Newcastle, NSW (B.C.), and the University of Sydney, Sydney (M.G.W.) - both in Australia; the University of Hong Kong, Queen Mary Hospital, Hong Kong (T.M.C.); Colorado Kidney Care, Denver (L.K.); Seoul National University College of Medicine, Seoul, South Korea (K.-H.O.); Osmania General Hospital, Hyderabad, India (M.S.); the Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo (Y.S.); and Otsuka Pharmaceutical Development and Commercialization, Princeton, NJ (J.X.).

概括

在12个月内,sibeprenlimab显著降低了IgA脏病患者的蛋白尿症. 这种新型抗体疗法为这种脏疾病提供了一种有前途的新疗法.