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Updated: Jun 28, 2026

Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging
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在全国样本中诊断轻链 Amyloidosis 的患者之旅:跨部分基于网络的研究

Xuelin Dou1, Yang Liu1, Aijun Liao2

  • 1Hematology Department, Peking University People's Hospital, Beijing, China.

JMIR formative research
|November 2, 2023
PubMed
概括

患有AL氨基粉症的中国患者由于各种症状而面临诊断延迟. 早期转诊到专门中心对于及时诊断和改善这种罕见疾病的管理至关重要.

关键词:
在AL氨基粉症症.大数据就是大数据.机器模型机器模型自然语言处理自然语言处理.网络分析 网络分析罕见病是一种罕见的疾病.系统性轻链氨基粉症.基于网络的基于网络的

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...
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Amyloid Fibrils

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