商业Delta-8 THC产品:内容和标签的分析
Eric E Kaczor1, Kevin Greene2, Kavita M Babu2
1Department of Emergency Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA. erickacz428@gmail.com.
概括
商用delta-8THC产品不受监管,分析显示标签不一致,delta-8四大麻素 (THC) 含量可变. 大多数产品含有麻醉剂量,广告和实际大麻素水平之间的差异很常见.
科学领域:
- 大麻素科学是关于大麻素的科学.
- 分析化学是一种分析化学.
- 公共卫生 公共卫生
背景情况:
- 德尔塔-8四大麻素 (THC) 是德尔塔-9THC的精神活性异构体,在法律上是不同的,但在商业上不受监管.
- 目前商业的delta-8THC产品在成分和标签上缺乏一致的监督.
- 这种监管差距引发了对产品安全和准确的消费者信息的担忧.
研究的目的:
- 描述零售delta-8THC产品的标签和广告做法.
- 量化比较广告中的delta-8THC含量与实验室验证的含量.
- 识别和量化这些产品中存在的其他大麻素.
主要方法:
- 在宾夕法尼亚州匹兹堡的零售店购买了20种delta-8THC产品.
- 采用经过验证的UPLC-MS/MS方法进行精确的大麻素含量分析.
- 利用描述性统计和相关性分析 (斯皮尔曼的rho) 来比较标记与分析的内容.
主要成果:
- 在95%的样本中检测到delta-8THC,在广告和实际内容之间存在微弱的正相关性 (rho=0.40).
- 固体矩阵 (,巧克力) 和缺乏"实验室测试"标签与较小的差异相关.
- 在35%的产品中发现了Delta-9 THC,在一种产品中发现了CBD.
结论:
- 分析的大部分delta-8THC产品含量足以引起中毒.
- 德尔塔-8THC含量的广泛变化以及与广告中的数量存在较弱的相关性凸显了标签上的不准确性.
- 检测到的大麻素仅限于delta-8THC,delta-9THC和CBD,表明测试产品中缺乏更广泛的大麻素多样性.
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