血压变化与急性缺血性中风中心脏病增长有关
Andrew G Woods1, Tom Lillicrap2,3, Rebecca Hood2,3
1School of Medicine, University of Notre Dame, Sydney, New South Wales, Australia, andrew.woods@my.nd.edu.au.
Cerebrovascular diseases (Basel, Switzerland)
|November 2, 2023
概括
急性缺血性中风期间的血压变化与较大的心脏病发作和脑出血风险增加有关. 管理血压变化对于改善患者的治疗结果至关重要.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
背景情况:
- 对急性缺血性中风缺乏基于证据的血压 (BP) 目标.
- 之前的研究集中在单个BP测量,忽视动态变化.
- 血压参数与中风结果之间的关联需要进一步调查.
研究的目的:
- 确定中风和心脏病发作期间血压参数 (变化,峰值,最低点,中位数,平均值) 之间的关联.
- 调查血压参数与出血变化的风险之间的关系.
- 评估BP参数对3个月后功能结果的影响.
主要方法:
- 从单个中风中心招募急性缺血性中风患者的前景招募.
- 多模式CT用于心脏病核心的定义;24小时后MRI用于心脏病的生长和出血的评估.
- 按指导方针记录的BP;使用修改的排名表在3个月后评估的功能结果.
主要成果:
- 血压变化 (BPV) 独立地与心脏病发作增长 (系数1.60) 和对瘤出血的更高几率 (OR1.21) 相关.
- 较高的BPV与90天后有利的功能结果相反相关.
- 在接受内血管凝块检索的大血管闭塞患者中,BPV与心脏病发育和出血转变有显著的关联.
结论:
- 在急性缺血性中风中,血压变化增加与心脏病扩张有关.
- BPV与出血转变的风险增加有关.
- 升高的BPV在中风后3个月对功能结果产生负面影响.
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