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A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
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抑制聚胺生物合成可以在1型糖尿病中保持β细胞功能

Emily K Sims1, Abhishek Kulkarni2, Audrey Hull3

  • 1Division of Pediatric Endocrinology and Diabetology, Herman B. Wells Center for Pediatric Research, Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Cell reports. Medicine
|November 2, 2023
PubMed
概括

通过保护β细胞,α-difluoromethylornithine (DFMO) 在延缓1型糖尿病 (T1D) 方面表现有前途. 这项研究证实了其安全性,并表明DFMO可能会在T1D患者中保持β细胞功能.

关键词:
疾病的修改 疾病的修改小岛小岛是一个小岛.甲氨酸脱碳酶酶是一种甲氨酸脱碳酶.聚氨酸是多氨基的预防 预防 预防试验试验试验试验试验试验试验第1类糖尿病 1型糖尿病α-二甲基诺尼丁氨酸是什么?一个β细胞β细胞.一个β细胞应激应变.

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