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Updated: Aug 12, 2026

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure
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RNA-seq分析显示,产前酒精暴露与胎盘炎症细胞和基因表达有关

Randy P Williams1, Corina Lesseur1, Haoxiang Cheng2

  • 1Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Gene
|November 2, 2023
PubMed
概括

产前酒精暴露 (PAE) 改变了胎盘细胞组成,增加了霍夫尔细胞和炎症基因表达. 这些发现突出了将PAE与胎儿酒精谱系障碍 (FASD) 联系起来的潜在机制.

关键词:
这就是 FASD 的原因.炎症 炎症是一种炎症.胎盘 胎盘 胎盘 胎盘产前暴露于酒精的情况.在RNA-seqqq.

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相关概念视频

Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...