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Updated: Jul 11, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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通过先进的糖化终产品对STING/TBK1/IRF3信号进行不同的调制

Takashi Nishinaka1, Omer Faruk Hatipoglu1, Hidenori Wake1

  • 1Department of Pharmacology, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

Archives of biochemistry and biophysics
|November 2, 2023
PubMed
概括

先进的糖化终产物 (AGEs) 通过调节STING/TBK1/IRF3信号来影响天生的免疫系统. AGEs对这种途径的影响取决于它们形成时使用的特定碳化合物,其中一些抑制信号,另一个增强信号.

关键词:
高级糖化最终产品的高级糖化.巨细胞是一个巨细胞.蛋白质修饰是一种蛋白质修饰.在STING/TBK1/IRF3信号传输中.

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