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在克洛扎治疗的精神分裂症中,强迫症症状和障碍
Jonathan Gerard Hsueh Ching Seow1, Deborah Hui Yi Tan1, Yuen Mei See2
1North Region, Institute of Mental Health, Singapore.
Spanish journal of psychiatry and mental health
|November 2, 2023
概括
强迫症症状 (OCS) 和强迫症 (OCD) 在接受克洛扎治疗的精神分裂症患者中很普遍. 年轻的年龄和早期的精神病发作与OCS有关,这需要临床医生进行常规查.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在精神分裂症患者中经常观察到强迫症症状 (OCS) 和强迫症 (OCD).
- 克洛扎宾是治疗耐药精神分裂症的药物,可能会诱发或加剧OCS/OCD.
- 有限的研究存在于OCS/OCD患病率和危险因素在克洛扎治疗精神分裂症.
研究的目的:
- 确定用克洛札治疗的精神分裂症患者中OCS和OCD的患病率.
- 在这个人群中确定与OCS和OCD相关的社会人口统计学,临床和治疗因素.
主要方法:
- 在新加坡一家三级精神病医院进行了横截面研究.
- 分析了159名被诊断为精神分裂症或精神分裂情绪障碍的患者,这些患者服用稳定的克洛扎宾剂量.
- 我们收集了社会人口统计,临床和治疗数据,并分析了与OCS/OCD的关联.
主要成果:
- 强迫症的患病率为21.4%,强迫症的患病率为12.6%.
- 年龄较小和精神病发作较早的年龄与OCS有关 (p<0.05).
- 没有任何显著的因素与强迫症相关,但年轻的年龄和早期的精神病发作与OCS/OCD结合有关.
结论:
- 在接受克洛扎治疗的精神分裂症患者中,有明显的OCS和OCD患病率.
- 临床医生应该考虑在这个患者群体中进行OCS/OCD的常规查.
- 需要进一步研究以了解已识别的风险因素及其与克洛扎治疗精神分裂症中OCS/OCD的联系.
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