BIS导向麻醉对儿童全身麻醉后出现妄想的作用:一项前性随机对照试验
Michal Frelich1, Karolína Lečbychová2, Vojtěch Vodička2
1Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Ostrava, Czechia; Department of Intensive Medicine, Emergency Medicine and Forensic Studies, Faculty of Medicine, University of Ostrava, Czechia.
用BIS监测麻醉深度有效地减少了接受腺切除术的儿童的出现妄想. 这种方法降低了PACU停留期间出现妄想 (ED) 的发生率和严重程度,改善了术后恢复.
科学领域:
- 儿科麻醉 儿科麻醉
- 神经麻醉的神经麻醉
- 术后并发症 术后并发症
背景情况:
- 出现妄想 (ED) 是儿科麻醉中常见的术后并发症,影响恢复.
- 吸入麻醉与更高的ED发病率有关.
- 临床试验注册:NCT04466579. 临床试验注册:NCT04466579. 临床试验注册:NCT04466579 临床试验注册
研究的目的:
- 调查使用BIS监视器定位全身麻醉深度是否可以降低儿科患者ED的发病率.
- 为了比较BIS导向麻醉和基于MAC的标准麻醉之间的ED发生和严重程度.
主要方法:
- 随机,前性,双盲研究,涉及163名年龄在3-8岁的儿童,接受了内镜腺切除术.
- 干预组:麻醉深度以BIS值为指导 (40-60). 对照组:以MAC和潮末度为指导的麻醉.
- 主要结局:在PACU期间发生ED. 二次结果:PAED分数在10分钟和30分钟,需要救援治疗.
主要成果:
- 与对照组 (35.1%) 相比,BIS指导组 (12.8%) 的ED发病率明显较低 (p=0.001).
- BIS监测导致麻醉后10分钟和30分钟的PAED得分较低 (p<0.001).
- 两组之间在需要救援治疗方面没有发现显著差异 (p=0.067).
结论:
- 个性化麻醉深度与BIS监测是预防儿科患者出现妄想的有效策略.
- BIS监测为优化麻醉管理和改善儿童手术后结果提供了有价值的工具.
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