大动脉周脉脂肪组织计算断层扫描衰减在患有大动脉狭窄症的患者
Simona B Botezatu1,2, Xinming Yu1, Mohammed N Meah1
1British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK.
Heart (British Cardiac Society)
|November 2, 2023
概括
大动脉周血管脂肪组织衰减的CT成像与大动脉狭窄症的严重程度或进展无关. 这一措施对于调查或管理大动脉狭窄患者来说是没有价值的.
科学领域:
- 心血管成像 - 心血管成像
- 放射学 放射学是一门学科.
- 炎症研究 炎症研究
背景情况:
- 大动脉狭窄 (AS) 与动脉样硬化有着共同的炎症途径.
- 周血管脂肪组织 (PVAT) CT衰减测量血管炎症,并预测预后.
- PVAT减弱在评估大动脉膜炎症方面具有潜在的应用.
研究的目的:
- 为了研究大动脉周血管脂肪组织 (PVAT) CT衰减在患有大动脉狭窄症 (AS) 的患者.
- 确定PVAT减弱与AS疾病严重程度,活性和进展之间的关联.
主要方法:
- 在患有AS和没有AS的患者中,CT衰减被测量为大动脉周围的PVAT.
- 分析了与AS严重程度 (心声图,CT分数),疾病活性 (18F-NaF PET) 和进展的关联.
主要成果:
- 大动脉PVAT减弱显示出高重复性,但在AS患者和对照患者中类似.
- 在轻度,中度或重度AS中没有发现PVAT减弱的差异.
- PVAT减弱与AS严重程度,活性或随后的进展无关.
结论:
- CT衍生的大动脉PVAT衰减与AS疾病的严重程度,活性或进展无关.
- 这种成像指标对AS患者的调查和管理没有价值.
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