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相关概念视频

Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

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The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
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Pulmonary Cycle: Exhalation01:17

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In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Breathing01:05

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The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
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Teratogenicity01:07

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
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相关实验视频

Updated: Jul 11, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
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遗传性肺部形 遗传性肺部形 遗传性肺部形

Federica Pederiva1, Steven S Rothenberg2, Nigel Hall3

  • 1Paediatric Surgery, "F. Del Ponte" Hospital, ASST Settelaghi, Varese, Italy. federica_pederiva@yahoo.it.

Nature reviews. Disease primers
|November 3, 2023
PubMed
概括
此摘要是机器生成的。

先天性肺形 (CLMs) 需要谨慎管理,关于无症状病例的手术干预与预期观察的持续辩论. 对它们的分子机制的进一步研究对于理解潜在的恶性转变至关重要.

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Transuterine Fetal Tracheal Occlusion Model in Mice
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Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

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相关实验视频

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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
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Transuterine Fetal Tracheal Occlusion Model in Mice
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科学领域:

  • 儿科手术 儿科手术
  • 胸部外科手术 胸部外科手术
  • 发展生物学 发展生物学

背景情况:

  • 先天性肺形 (CLMs) 是一种罕见的肺异常,影响1万例活产中的4例.
  • 呈现的情况从无症状到严重的呼吸衰竭各不相同.
  • 诊断通常包括产前超声波和产后CT血管造影.

研究的目的:

  • 审查CLM目前的诊断和管理策略.
  • 探索CLM发展和恶性转变背后的分子机制.
  • 为了确定在CLM护理中的关键未回答的问题.

主要方法:

  • 关于CLM诊断,治疗和分子病理学的文献综述.
  • 分析当前的手术与非手术治疗方法.
  • 关于遗传因素的研究摘要,包括CPAM中的KRAS突变.

主要成果:

  • 手术切除是症状性CLM的标准,降低了发病率和恶性瘤风险.
  • 关于管理无症状的CLM缺乏共识,关于切除与观察的争论正在进行中.
  • 分子研究正在探索遗传易感性和恶性转变途径.

结论:

  • 无症状的CLM的最佳管理仍未确定.
  • 对所有CLM患者来说,有计划的随访和过渡到成人护理是必不可少的.
  • 了解CLM的分子基础对于未来的治疗策略和风险评估至关重要.