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Updated: Jul 11, 2025

Development of an Insert Co-culture System of Two Cellular Types in the Absence of Cell-Cell Contact
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葡萄皮质类药物通过A549细胞中的Bcl-2/GR复合体缓解颗粒物诱导的COX-2表达和线粒体功能障碍

Yeon-Ji Park1,2, June Heo1,2, Yonghyeon Kim1,2

  • 1Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Republic of Korea.

Scientific reports
|November 3, 2023
PubMed
概括

葡萄糖皮质类药物通过葡萄糖皮质类受体 (GR) 调节循环氧化酶-2 (COX-2) 途径和线粒体功能,抑制颗粒物 (PM) 诱导的肺炎. 这涉及减少活性氧物种 (ROS) 和增强Bcl-2/GR复合体.

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