预测术后疼痛和切除术后生活质量的参数:从前性多中心随机试验的后续结果
Christoph Mallmann1, Mike Ralf Langenbach2, Razvan-Valentin Florescu3
1Department of General, Visceral and Oncological Surgery, Helios University Hospital Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.
International journal of colorectal disease
|November 3, 2023
概括
较年轻的患者经历了更多的疼痛后出血切除术,这可以通过避免吸血栓和使用 pudendal 阻塞减少. 早期疼痛管理是改善手术后生活质量的关键.
科学领域:
- 外科手术的结果
- 疼痛管理 疼痛管理
- 生活质量生活的质量.
背景情况:
- 淋病切除术与严重的术后疼痛和降低生活质量 (QoL) 相关.
- 经过切除术后疼痛和QoL的预测因素需要进一步调查,以优化患者护理.
- 试验的注册:DRKS00011590.0. 试验的注册:DRKS00011590. 试验的注册:DRKS00011590. 试验的注册:DRKS00011590.
研究的目的:
- 为了确定术后疼痛和经过切除术后 QoL 的预测参数.
- 了解影响切除术后早期和晚期疼痛的因素.
- 为了探索血切除术后生活质量变化的预测因素.
主要方法:
- 一个多中心随机对照试验的后续分析,涉及770名患者.
- 手术前,手术内和手术后的参数与疼痛 (NRS) 和 QoL (EuroQuol) 的相关性.
- 单变量和多变量分析以确定重要的预测因素.
主要成果:
- 年龄较小,使用带,术前疼痛和布丁达阻塞与早期术后疼痛有关.
- 不使用布登达尔阻塞,年龄较小,使用带,以及手术前的疼痛预测了相关的早期疼痛.
- 手术后7天的相关疼痛与早期疼痛有关; QoL变化与疼痛减轻和阿片类药物使用有关.
结论:
- 年轻患者的早期术后疼痛可以通过避免吸管和使用布登达尔阻塞来减轻.
- 一周后持续的疼痛主要与早期的术后疼痛有关.
- 改善血切除术后的生活质量包括管理现有的疼痛和使用阿片类止痛药.
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