Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Proteomics01:33

Proteomics

7.4K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Unraveling the role of lactylation in cell death and correlative diseases: a comprehensive review.

Frontiers in cell and developmental biology·2026
Same author

HNRNPA0 Acts as a Master Upstream Regulator of NF-κB to Drive Oncogenic Phenotypes in Oral Squamous Cell Carcinoma.

International dental journal·2026
Same author

TRUST: A toolkit for TEE-assisted secure outsourced computation over integers.

Fundamental research·2026
Same author

Uncovering the Key Circuit FOSL2/FOS/EGR3/EGR1, Contributing to the Hyperexcitability of Excitatory Neurons in the Epileptic Temporal Cortex and Hippocampus.

International journal of molecular sciences·2026
Same author

MixNet: A scale-adaptive method for multivariate time series forecasting.

PloS one·2026
Same author

How Does Right Atrial Function Differ? A Speckle-Tracking Echocardiographic Comparison of Fetuses With Left Ventricular Outflow Tract Obstruction Versus Those With Significant Tricuspid Regurgitation.

Echocardiography (Mount Kisco, N.Y.)·2026

相关实验视频

Updated: Jul 11, 2025

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.4K

使用 mip-mining 数据库探索来自各种模型生物的微蛋白.

Bowen Zhao1, Jing Zhao1, Muyao Wang1

  • 1State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.

BMC genomics
|November 3, 2023
PubMed
概括

Mip-mining是一个新的数据库,用于使用RNA测序数据探索微蛋白功能. 它有助于理解微蛋白在健康,压力和生物技术应用中的作用.

关键词:
疾病 疾病 疾病微蛋白质是一种微蛋白质.在Mip-mining数据库中挖掘数据.在RNA-Seqq.压力反应应对压力.

更多相关视频

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
09:52

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

Published on: January 10, 2025

627
Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames
07:38

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

12.8K

相关实验视频

Last Updated: Jul 11, 2025

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.4K
A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
09:52

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

Published on: January 10, 2025

627
Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames
07:38

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

12.8K

科学领域:

  • 分子生物学分子生物学
  • 基因组学就是基因组学.
  • 生物技术是生物技术.

背景情况:

  • 微蛋白对生命至关重要,影响细胞生理学和人类健康.
  • 转录组数据丰富,但微蛋白功能洞察力仍然有限.
  • 现有的资源并没有专门专注于从转录基因数据中进行微蛋白功能分析.

研究的目的:

  • 引入Mip-mining,这是一个用于分析微蛋白功能的新型数据库.
  • 为微蛋白研究提供利用高质量的RNA测序数据的资源.
  • 为了促进微蛋白在各种生物环境中的作用的探索.

主要方法:

  • 汇编了336个高质量的转录组数据集,来自9个物种的8626个样本.
  • 包括涵盖各种压力条件 (化学,物理,生物,疾病相关) 的数据.
  • 开发一个平台,以用户定义的参数进行定制分析.

主要成果:

  • Mip-mining拥有广泛的转录组数据,专注于微蛋白质.
  • 该数据库可以识别不同物种中必需的微蛋白.
  • 证明了ATP15在酸应激耐受性中的作用.

结论:

  • Mip-mining显著提高了对微蛋白功能的理解.
  • 该数据库支持生物技术应用和治疗策略的开发.
  • 促进研究微蛋白在各种环境和疾病条件下的作用.