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神经性厌食症和避免/限制性食物摄入障碍患者的维生素D和低酸血症:一个病例对照研究
Meredith R Kells1,2, Chloe Roske3,4, Ashlie Watters5,6
1Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA. Meredith_Kells@URMC.Rochester.edu.
Journal of eating disorders
|November 3, 2023
概括
重新食低度症 (RH) 影响了超过三分之一的精神性厌食症 (AN) 或避免/限制性食物摄入障碍 (ARFID) 患者. 维生素D水平影响水平,可能会影响这些人群的RH发展.
科学领域:
- 营养精神病学 营养精神病学
- 内分泌学 在内分泌学.
- 胃肠病学 胃肠病学
背景情况:
- 再养低血症 (RH) 是营养康复过程中常见的并发症营养不良患者.
- 患有神经性厌食症 (AN) 和避免/限制性食物摄入障碍 (ARFID) 的个人经常表现出维生素D缺乏,影响的吸收.
- 在AN和ARFID种群中,维生素D在RH中的特定作用仍然未被描述.
研究的目的:
- 为了确定患有AN和ARFID的患者中低维生素D和RH的患病率.
- 探索血清和与RH相关的因素之间的关联.
- 为了研究维生素D水平与RH之间的关系,以及其对平衡的适度作用.
主要方法:
- 对307名被诊断患有AN或ARFID的患者进行了回顾性图表审查.
- 对入院实验室值的分析,包括25-基维生素D和血清.
- 使用相关性,ANOVA和回归来评估变量关系的统计分析.
主要成果:
- 超过三分之一 (35.3%) 的样本经历过低血症 (血清≤2.9 mg/dL).
- 在35%的ARFID患者和29%的AN患者中观察到维生素D缺乏或不足.
- 较高的25-基维生素D水平减轻了入院体重和血清的最低值之间的关联.
结论:
- 患有ARFID的患者在维生素D和RH方面表现出与AN患者相似的营养脆弱性.
- 维生素D可能在调节平衡中发挥关键作用,影响AN和ARFID中的RH发育.
- 研究结果表明,可能存在一种负反循环,其中包括维生素D参与RH的发病.
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