改善香料的抗氧化活性需要丰富不同的,但密切相关的代谢途径
Sonia Gandhi1, Manas Ranjan Saha2, Priyankar Dey1
1Department of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, Punjab, India.
Heliyon
|November 3, 2023
概括
研究人员开发了一种反向关联策略,以确定植物代谢途径,以提高植物化学物质的生产. 这种方法将植物化学特征与特定途径联系起来,提高了抗氧化剂香料的质量.
科学领域:
- 植物生物化学 植物生物化学
- 代谢工程是代谢工程.
- 植物化学分析 植物化学分析
背景情况:
- 基因和代谢工程为改善作物中的植物代谢物生物合成提供了策略.
- 相互连接的代谢途径在确定特定生物活性的目标方面带来了挑战.
研究的目的:
- 提出和验证一个反向关联策略,以确定基于植物化学特征的目标代谢途径.
- 增强商业和药理相关植物代谢物质的生产.
主要方法:
- 非定位气色谱-质谱 (GC-MS) 植物化学分析阿皮亚ceae家族的种子 (Coriandrum sativum,Trachyspermum ammi,Cuminum cyminum,Foeniculum vulgare). 没有目标的气色谱-质谱.
- 使用多个抗氧化剂试验评估整体抗氧化剂概况.
- 生物信息学方法用于识别植物化学类和丰富的生物合成途径.
主要成果:
- 该研究确定了丰富的异oprenoid 和脂肪酸生物合成途径.
- 在特定的代谢途径和抗氧化能力之间发现了强烈的关联.
- 反向关联策略成功将植物化学特征与潜在的代谢标联系起来.
结论:
- 丰富特定的,相互关联的代谢途径可以改善香料质量和抗氧化作用.
- 拟议的逆关联策略有效地识别了增强植物代谢物的向途径.
- 这种方法有助于改善作物以生产有价值的植物化学物质.
更多相关视频
07:59A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
9.8K
11:44Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
Published on: January 19, 2022
2.5K
相关概念视频
01:20Radical Autoxidation
2.2K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.2K
01:20Sulfur Assimilation
20
Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
20
01:17Oxidation of Phenols to Quinones
3.1K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
3.1K
01:27Redox Reactions
19
Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
19
01:29Amino Acid Biosynthetic Pathways
17
Amino acid biosynthesis is essential for cell growth, protein synthesis, and metabolic regulation. Cells generate essential and non-essential amino acids from metabolic intermediates to sustain vital biological functions. These intermediates originate from key metabolic pathways: glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway. Important precursors include α-ketoglutarate, pyruvate, oxaloacetate, phosphoenolpyruvate, and erythrose-4-phosphate, which...
17
01:40Overview of Metabolism
30.4K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
30.4K