神经胃大麻学:调节情绪和消化健康的新范式
Fabio Turco1, Viola Brugnatelli1, Raquel Abalo2,3,4
1Cannabiscientia SA, Lugano, Switzerland.
Medical cannabis and cannabinoids
|November 3, 2023
概括
内分泌大麻素系统 (ECS) 调节肠道健康和情绪. 新的神经胃大麻学建议使用益生菌,益生菌或植物大麻素来治疗肠道疾病和情绪失衡.
科学领域:
- 胃肠病学 胃肠病学
- 神经科学是一个神经科学.
- 微生物学 微生物学
背景情况:
- 内分泌系统 (ECS) 对于维持胃肠道 (GI) 恒温至关重要,它调节运动,分泌和疼痛等功能.
- 中枢神经系统影响中枢神经系统功能,影响食物摄入量和能量平衡,并与肠道微生物群双向相互作用.
- 胃肠道功能障碍,情绪障碍和ECS之间存在着强烈的联系,微生物群影响ECS基调,反之亦然.
研究的目的:
- 引入神经胃大麻学作为理解和治疗情绪相关的胃肠道疾病和胃肠道相关的情绪障碍的新范式.
- 探索调节ECS和肠道微生物群的治疗潜力,以改善心理和消化健康.
主要方法:
- 这篇迷你综述综合了ECS,肠道微生物群及其与大脑和肠道功能的相互作用的现有证据.
- 它提出了一个概念框架,将这些元素整合到治疗策略中.
主要成果:
- 肠道神经系统在调节影响肠道功能的神经传递方面发挥着重要作用,并受到肠道微生物群的影响.
- 肠-ECS-大脑轴的功能障碍与肠道疾病和情绪障碍的并发症有关.
结论:
- 神经胃大麻学提供了一种新的方法,通过建议干预措施,如益生菌,益生菌,植物性大麻素,或内分泌类型的分子 (例如,棕甲基乙醇胺).
- 这些干预措施旨在恢复ECS音调和微生物群平衡,可能同时缓解情绪和胃肠道症状.
相关概念视频
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01:25Regulation of the Digestive System
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