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Updated: Jul 11, 2025

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

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通过基甲基-γ尾巴片核酸的DNA识别和诱导基因组修饰

Stanley N Oyaghire1,2, Elias Quijano3,4,2, J Dinithi R Perera1

  • 1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Cell reports. Physical science
|November 3, 2023
PubMed
概括

新的核酸 (PNA) 修改增强了基因编辑. 氧甲基-γPNA在小鼠细胞中对再组合诱导的基因修饰的疗效和安全性得到改善.

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Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures08:15

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

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Maxam-Gilbert Sequencing

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