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用层次数据评估风险预测:对AUC的依赖性调整的信心区间
Camden Bay1, Robert J Glynn1, Johanna M Seddon2
1Harvard Medical School, Brigham and Women's Hospital, Boston, MA, 02115, USA.
概括
本研究将分析接收器操作特征曲线 (AUC) 下面区域的方法扩展到三级层次数据. 新方法可以在复杂的集群数据结构中对AUC进行可靠的统计推断.
科学领域:
- 生物统计学 生物统计学
- 统计建模 统计建模
- 机器学习评估 机器学习评估
背景情况:
- 真正ROC曲线下的面积 (AUC) 是二进制结果歧视的一个关键指标.
- 标准AUC推断假定独立的结果,限制其使用与层次数据.
- 现有的方法处理的是两层层次的层次数据,而不是更复杂的结构.
研究的目的:
- 将AUC推断方法扩展到三级层次数据.
- 开发一种强大的方法来处理AUC分析中的绑定预测得分.
- 在复杂的集群数据中提供可靠的统计推理方法.
主要方法:
- 开发了通用估计方程 (GEE) 模型的扩展,采用探针转换得分.
- 结合了一种方法来解释绑定的预测得分.
- 模拟了三级集群数据,集群大小不同,数据绑定.
主要成果:
- 拟议的方法证明了AUC (0.943-0.958) 的准确95%置信区间覆盖率.
- 理论和经验AUC差异的比率接近1 (0.920-1.013).
- 性能超过了对等级数据的现有AUC推断方法.
结论:
- 新的方法允许在三级层次的等级设置中进行有效的AUC推断.
- 该方法对绑定预测得分和可变集群大小具有稳定性.
- 这项工作促进了复杂数据结构中预测模型的统计评估.
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