金属DNA纳米复合物通过抑制自介导抵抗来增强化学动态疗法

Chao Gu1,2, Xueliang Liu2, Lei Luo2

  • 1Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, P. R. China.

概括

这项研究引入了金属-DNA纳米复合物 (DACs-Mn),通过抑制癌细胞自我保护机制自而增强癌症化学动态治疗 (CDT). 这种方法提高了CDT的疗效,并通过诱导免疫细胞死亡来抑制瘤转移.

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