代际传播ADHD行为:遗传和环境途径
Thomas H Kleppesto1,2, Espen Moen Eilertsen1,3,4, Elsje van Bergen5,6,7
1Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Psychological medicine
|November 3, 2023
概括
遗传因素主要解释了父母和孩子之间注意力缺陷多动症 (ADHD) 行为的相似性. 环境影响和家长的行为在这种代际传播中起到最小的作用.
科学领域:
- 行为遗传学 行为遗传学
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 父母和儿童的注意力缺陷多动症 (ADHD) 行为表现出共同变异.
- 了解多动症行为跨代传播至关重要.
研究的目的:
- 调查遗传和/或环境因素是否解释了父母和孩子ADHD行为之间的共变性.
- 为了解开多动症行为的代际影响.
主要方法:
- 使用了挪威大型母亲,父亲和儿童队列研究样本 (N = 22,276名父母,11,566名儿童).
- 采用双胞胎和兄弟姐妹的孩子设计来区分遗传和环境传播.
- 收集了父母报告的母亲,父亲和他们的8岁孩子的ADHD症状.
主要成果:
- 儿童ADHD行为与母亲 (0.24) 和父亲 (0.10) 的ADHD行为相关.
- 添加基因传输在很大程度上解释了这些相关性.
- 儿童ADHD行为遗传率为57% (11%来自父母基因,46%来自儿童特异性基因).
- 环境传播和基因环境相关性影响很小 (分别为2%和3%).
结论:
- 在ADHD行为中,代际相似性主要是由遗传传染驱动的.
- 很少有证据支持父母的ADHD行为直接导致孩子的ADHD行为.
- 这些发现挑战了多动症代际传播的环境理论,包括育儿和生活史理论.
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