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Updated: Jul 11, 2025

Stimulation of Notch Signaling in Mouse Osteoclast Precursors
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Hdac1和Hdac2积极调节雄性小鼠在已致性骨质母细胞中的Notch1功能获取致病信号

Haydee M Torres1,2,3, Leetoria Hinojosa1, Ashley M VanCleave1

  • 1Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, South Dakota, USA.

Birth defects research
|November 3, 2023
PubMed
概括

基因组脱乙酶1和2 (HDAC1/2) 在骨发育中促进Notch1信号传递. 在小鼠中删除HDAC1/2部分逆转了骨质硬化症,一种骨疾病,表明骨疾病中的作用.

关键词:
在 HDAC1 中,HDAC1 是在 HDAC2 中.标记1 标记1 标记表观遗传学是指表观遗传学.骨质母细胞的骨质母细胞.骨质硬化症 骨质硬化症

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