在心肺复苏期间对气溶生成的定量评估
A J Shrimpton1, V Brown2,3, J Vassallo4,5
1Anaesthesia, Pain and Critical Care Sciences, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Anaesthesia
|November 3, 2023
概括
心肺复苏 (CPR) 产生大量的呼吸气溶,增加了通过空气传播疾病的传播风险. 对于高风险的病原体,建议采取空气中的预防措施,直到先进的气道得到保护.
科学领域:
- 紧急医疗 紧急医疗
- 传染病控制和控制传染病
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 心肺复苏 (CPR) 对心脏骤停的生存至关重要.
- 肺复苏的气溶产生潜力以及医疗保健工作者面临的相关风险仍然不清楚.
- 在心肺复苏期间采取的空气传播预防措施可能会保护救援人员,但可能会延迟患者的治疗.
研究的目的:
- 在人类心肺复苏过程中量化呼吸气溶的产生.
- 为了确定有助于气溶化的特定CPR组件.
- 评估在非医院心脏骤停期间空气传播疾病传播的风险.
主要方法:
- 在人类 (n=18) 的非医院心脏骤停期间进行了气溶监测研究.
- 使用光学粒子测量器光谱仪测量在CPR期间呼出的气溶.
- 采用猪心脏骤停模型来隔离气溶产生的通风,胸部压缩和除.
主要成果:
- 在心肺复苏期间的通风产生了与麻醉下的对照组相比24倍高的气溶度 (17,926比744颗粒/L).
- 在心脏除和胸部压缩期间也观察到显著的气溶增加.
- 一个猪模型证实了类似的气溶化模式和CPR组件之间的协同效应.
结论:
- 心肺复苏的多个组成部分,包括通风,胸部压力和除,产生高度的呼吸气溶.
- 对于涉及高风险病原体的CPR,建议采取空气传播预防措施.
- 这些预防措施应保持,直到先进的气道装置和过呼吸系统到位.
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